The preparation of a Sodium Alginate Gel Practical is an easy process in a pharmaceutics laboratory. Here we provide details to prepare and submit 30gm of Sodium Alginate Gel Practical.
Sodium Alginate Gel practicals are included in D pharmacy 1st-year Pharmaceutics I subjects. After completing the practical students should be able to know how to prepare Sodium Alginate Gel in a pharmacy.
In this article, we provide A Practical Manual of Pharmaceutics from start to end, like title, aim, references, requirements, theory, procedure, and results. You just need to write your practical in your practical notebook. Don’t need to search further regarding this practical in any book.
Sodium Alginate Gel Practical
Title:-
Prepare and submit Sodium Alginate Gel Practical.
Aim:-
To prepare and submit 30gm of Sodium alginate gel.
Reference:-
1. Pharmacopoeia of India
Requirements:-
Apparatus Required: Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, etc.
Chemical Required: Sodium alginate, Calcium chloride, Coloring agent, purified water
Sodium Alginate Gel Theory:-
A gel is a semi-solid substance that can have properties ranging from soft and weak to hard and tough. Gels are defined as an essentially dilute cross-linked system that exhibits no flow at a steady state. A gel has been phenomenologically defined as a soft, hard, or solid material consisting of two or more components, one of which is a liquid, present in substantial amounts.
| Sr No | Ingredients | Official Formula(I.P.) | Working Formula | Required Quantity |
|---|---|---|---|---|
| 1 | Sodium alginate | 2%w/v | – | – |
| 2 | Calcium chloride | 5%w/v | – | – |
| 3 | Calcium chloride | q. s | – | – |
| 4 | Purified water | 100ml | – | 30gm |
Calculations:-
Procedure:-
Sodium alginate gel formation is discussed below;
Step 1: Mix dry sodium alginate powder with distilled water
For a great gel, use 100 ml of distilled water and 1 teaspoon of sodium alginate (this is a 2% solution of sodium alginate).
Step 2: In another container, mix calcium chloride with distilled water
Use a heaping teaspoon of calcium chloride in 100 ml of distilled water (this is a 5% calcium chloride solution)
Step 3: Create a gel by adding dissolved alginate to the calcium solution
Using a spoon or dropper, add (i.e., drip or spray) some of the sodium alginate solution to the calcium chloride solution. The calcium instantly reacts with the sugar units in the alginate and pulls the long flexible chains of the alginate into a gel.
What is the category of Sodium Alginate Gel:-
Sodium Alginate Gel acts as a Scabicide.
Sodium Alginate Gel uses:-
Sodium Alginate Gel uses as an emulsifier or stabilizer.
Storage:-
Sodium Alginate Gel should be tightly closed and stored out of contact with water.
Direction:-
To be applied on dry skin three times a day.
Label:-
Sodium Alginate Gel label are;
| Medicine Name | Sodium Alginate Gel 30gm |
| Composition: Sodium alginate Calcium chloride Colouring agent Purified water | BATCH NO.: MFG. DATE: EXPIRY DATE: |
| – | FOR EXTERNAL USE ONLY |
| Category: | Stabilizing |
| Use: | used as an emulsifying, stabilizing, suspending, thickening in |
| Storage: | Stored in a well closed container at a temperature not exceeding 250C It should be tightly closed and stored out of contact with water |
| MFG BY: ABCD | Batch/Section: Roll No.: |
Report:-
30gm of Sodium Alginate Gel Practical is Prepared and Submitted.
Some FAQs Related To Sodium Alginate Gel Practical
What is Sodium Alginate Gel Practical?
Ans. Alginate gel is used as a lubricant and dermatological vehicle. The viscosity of sodium alginate gel can be increased by adding soluble calcium gluconate. Sodium alginate has an advantage over tragacanth in that it is available in several grades of standardized viscosity.
How to Prepare Sodium Alginate Gel?
Ans. Formulation and Evaluation of Sodium Alginate Beads, you can:
Mix 1 teaspoon of sodium alginate with 100 milliliters of distilled water. This creates a 2% sodium alginate solution.
Stir the mixture with a spoon for about 30 minutes to dissolve the sodium alginate.
Alternatively, you can mix 2 grams of sodium alginate with 100 milliliters of deionized or distilled water in a blender. Stir for about 15 minutes or until all the sodium alginate has dissolved
What are the uses of Sodium Alginate Gel?
Ans. Sodium alginate is a water-soluble polysaccharide used in food and cosmetics. It is extracted from brown seaweed and is used as a thickener, stabilizer and gelling agent. It can be used in a variety of foods including: sauces, salad dressings, cheese products, instant noodles, beer.
How to Download Sodium Alginate Gel Practical Pdf?
Ans. You can download the Sodium alginate gel practical slideshare by clicking on the “download now” button given below. Sodium alginate gel practical manual pdf and Sodium alginate gel practical notes are also given in the pdf.
What is the role of calcium gluconate in sodium alginate gel?
Ans. The desired flavored and colored sodium alginate solution is dripped into the calcium solution. Calcium ions enter the alginate droplet and replace Na + ions, which leads to the cross-linking of Ca +2 ions and their transformation into a gel matrix, which is further hardened in a calcium solution.
How do you harden alginate gel?
Ans. To harden the alginate gel, you can immerse it in a calcium chloride (CaCl2) solution. The calcium ions in the solution react with the alginate to form a gel. The gelation process occurs when calcium ions are inserted between the alginate strands, allowing them to bond with each other.
The ratio of alginate solution to CaCl2 solution used for gel beads is 4:3 and 1:4 (wt/wt).
Alginate gel hardens as it dries. It is easier to remove the alginate in the first few minutes because it hardens as it dries.
Pharmaceutics I Related Other Practicals Lab Manual
Conclusion
Pharmaceutics I is the most important subject for D Pharmacy 1st year students. This subject comprises both theory and practical portions and you should give a university exam as well as an internal exam for both. Here we provided all the Sodium Alginate Gel Pharmaceutics Lab Practical Manual details as per the PCI syllabus.
Here we define Sodium Alginate Gel and its method of preparation. If Sodium Alginate Gel Practical is helpful for you, please share your valuable concerns.