Pharmaceutical Chemistry Notes PDF Download D.Pharm 1st Year

PHARMACEUTICAL CHEMISTRY CHAPTER-WISE NOTES ER20-12T

CHAPTER – 1

• Introduction to Pharmaceutical chemistry: Scope and objectives
• Sources and types of errors: Accuracy, precision, significant figures
• Impurities in Pharmaceuticals: Source and effect of impurities in Pharmacopeial substances, importance of limit test, Principle and procedures of Limit tests for
• chlorides, sulphates, iron, heavy metals and arsenic.

CHAPTER – 2

• Volumetric analysis: Fundamentals of volumetric analysis, Acid-base titration, non-aqueous titration, precipitation titration, complexometric titration, redox titration
• Gravimetric analysis: Principle and method.

CHAPTER – 3

• Inorganic Pharmaceuticals: Pharmaceutical formulations, market preparations, storage conditions and uses of
• Haematinics: Ferrous sulphate, Ferrous fumarate, Ferric ammonium citrate, Ferrous ascorbate, Carbonyl iron
• Gastro-intestinal Agents: Antacids; Aluminium hydroxide gel, Magnesium hydroxide, Magaldrate, Sodium bicarbonate, Calcium Carbonate, Acidifying agents, Adsorbents, Protectives, Cathartics
• Topical agents: Silver Nitrate, Ionic Silver, Chlorhexidine Gluconate, Hydrogen peroxide, Boric acid, Bleaching powder, Potassium permanganate
• Dental products: Calcium carbonate, Sodium fluoride, Denture cleaners, Denture adhesives, Mouth washes
• Medicinal gases: Carbon dioxide, nitrous oxide, oxygen

CHAPTER – 4

• Introduction to nomenclature of organic chemical systems with particular reference to heterocyclic compounds containing up to Three rings

CHAPTER – 5

• Drugs Acting on the Central Nervous System
• Anaesthetics: Thiopental Sodium, Ketamine Hydrochloride, Propofol
• Sedatives and Hypnotics: Diazepam, Alprazolam, Nitrazepam, Phenobarbital*
• Antipsychotics: Chlorpromazine Hydrochloride, Haloperidol, Risperidone, Sulpiride, Olanzapine, Quetiapine, Lurasidone
• Anticonvulsants: Phenytoin, Carbamazepine, Clonazepam, Valproic Acid, Gabapentin, Topiramate, Vigabatrin, Lamotrigine
• Anti-Depressants: Amitriptyline Hydrochloride, Imipramine Hydrochloride, Fluoxetine*, Venlafaxine, Duloxetine, Sertraline, Citalopram, Escitalopram, Fluvoxamine, Paroxetine

CHAPTER – 6

• Drugs Acting on Autonomic Nervous System
• Sympathomimetic Agents: Direct Acting: NorEpinephrine, Epinephrine, Phenylephrine, Dopamine, Terbutaline, Salbutamol (Albuterol), Naphazoline, Tetrahydrozoline Indirect Acting Agents: Hydroxy Amphetamine, Pseudoephedrine.
• Agents With Mixed Mechanism: Ephedrine, Metaraminol
• Adrenergic Antagonists: Alpha Adrenergic Blockers: Tolazoline, Phentolamine Phenoxybenzamine, Prazosin.
• Beta Adrenergic Blockers: Propranolol, Atenolol, Carvedilol
• Cholinergic Drugs and Related Agents: Direct Acting Agents: Acetylcholine, Carbachol, And Pilocarpine
• Cholinesterase Inhibitors: Neostigmine, Edrophonium Chloride, Tacrine Hydrochloride, Pralidoxime Chloride, Echothiopate Iodide Cholinergic Blocking Agents: Atropine Sulphate, Ipratropium Bromide
• Synthetic Cholinergic Blocking Agents: Tropicamide, Cyclopentolate Hydrochloride, Clidinium Bromide, Dicyclomine Hydrochloride*

CHAPTER – 7

• Drugs Acting on Cardiovascular System
• Anti-Arrhythmic Drugs: Quinidine Sulphate, Procainamide Hydrochloride, Verapamil, Phenytoin Sodium, Lidocaine Hydrochloride, Lorcainide Hydrochloride, Amiodarone and Sotalol Anti-Hypertensive Agents: Propranolol, Captopril*, Ramipril, Methyldopate Hydrochloride, Clonidine Hydrochloride, Hydralazine Hydrochloride, Nifedipine,
• Antianginal Agents: Isosorbide Dinitrate

CHAPTER – 8

• Diuretics: Acetazolamide, Frusemide*, Bumetanide, Chlorthalidone, Benzthiazide, Metolazone, Xipamide, Spironolactone

CHAPTER – 9

• Hypoglycemic Agents: Insulin and Its Preparations, Metformin, Glibenclamide, Glimepiride, Pioglitazone, Repaglinide, Gliflozins, Gliptins

CHAPTER – 10

• Analgesic And Anti-Inflammatory Agents: Morphine Analogues, Narcotic Antagonists
• Nonsteroidal Anti-Inflammatory Agents (NSAIDs) – Aspirin, Diclofenac, Ibuprofen, Piroxicam, Celecoxib, Mefenamic Acid, Paracetamol*, Aceclofenac

CHAPTER – 11

• Anti-Infective Agents
• Antifungal Agents: Amphotericin-B, Griseofulvin, Miconazole, Ketoconazole, Itraconazole, Fluconazole, Naftifine Hydrochloride
• Urinary Tract Anti-Infective Agents: Norfloxacin, Ciprofloxacin, Ofloxacin, Moxifloxacin,
• Anti-Tubercular Agents: INH, Ethambutol, Para Amino Salicylic Acid, Pyrazinamide, Rifampicin, Bedaquiline, Delamanid, Pretomanid*
• Antiviral Agents: Amantadine Hydrochloride, Idoxuridine, Acyclovir, Foscarnet, Zidovudine, Ribavirin, Remdesivir, Favipiravir
• Antimalarials: Quinine Sulphate, Chloroquine Phosphate, Primaquine Phosphate, Mefloquine, Cycloguanil, Pyrimethamine, Artemisinin
• Sulfonamides: Sulfanilamide, Sulfadiazine, Sulfamethoxazole, Sulfacetamide, Mafenide Acetate, Cotrimoxazole, Dapsone*

CHAPTER – 12

• Antibiotics: Penicillin G, Amoxicillin, Cloxacillin, Streptomycin,
• Tetracyclines: Doxycycline, Minocycline
• Macrolides: Erythromycin, Azithromycin
• Miscellaneous: Chloramphenicol Clindamycin

CHAPTER – 13

• Anti-Neoplastic Agents: Cyclophosphamide, Busulfan, Mercaptopurine, Fluorouracil, Methotrexate, Dactinomycin, Doxorubicin Hydrochloride, Vinblastine Sulphate, Cisplatin*, Dromostanolone Propionate