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Impure Chemical Compound: A compound is said to be impure if it is having foreign matter i.e. Impurities.
Pure Chemical Compound: A pure chemical compound refers to a compound which is having no foreign matter i.e. impurities. Chemical purity means freedom from foreign matter.
Analytically 100 % pure substances are not available and traces of impurities must be present.
Normally undesirable foreign materials are present in pharmaceutical substances.
• Impurity is any material that affects the purity of the material of interest.
• Presence of Impurities in pharmaceutical substances may produce toxic effects on the body and may also lower the active strength of the pharmaceutical substance.
• Impurities commonly in chemical substances include small quantities of lead, Chloride, and sulfate.
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Sources of Impurities Notes Includes Topics
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- The raw material used in the manufacture
- Reagents used in the manufacturing process
- Method/ process in manufacture or method of manufacturing
- Chemical processes used in the manufacture
Atmospheric contamination during the manufacturing process, Intermediate products in the manufacturing process, Defects in the manufacturing process, Manufacturing hazards, and Inadequate Storage conditions.
Decomposition of the product during storage, Accidental substitution, or deliberate adulteration with spurious or useless materials.
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