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A eutectic mixture is defined as a mixture of two or more components that usually do not interact to form a new chemical compound but, at certain ratios, inhibit the crystallization process of one another resulting in a system having a lower melting point than either of the components.
Eutectic mixtures can be formed between Active Pharmaceutical Ingredients (APIs), between APIs and excipients, or between excipients; thereby providing a vast scope for its applications pharmaceutical industry.
Eutectic mixture formation is usually governed by the following factors:
(a) The components must be miscible in a liquid state and mostly immiscible in a solid
state.
(b) Intimate contact between eutectic forming materials is necessary for contact-induced melting point depression
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- Definition
- Example
- Problem Solutions
- Application of Eutectic Mixtures in the Pharmaceutical Industry
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