ESSENTIALS OF MEDICAL PHARMACOLOGY (COVERING COMPETENCY-BASED NMC CURRICULUM)
| Author’s Name | KD Tripathi |
| Editions | Latest Edition |
| Publishers | Jaypee Brothers Medical Publishers Pvt. Ltd. |
Pharmacology 1 [For Second Year B.Pharmacy – Semester 4 – As Per PCI Syllabus
| Author’s Name | Dr. Adhikrao V. Yadav, Dr. Atul R. Chopade |
| Editions | Latest Edition |
| Publishers | Nirali Prakashan |
Pharmacology I for B. PHARMACY PCI 17 (IV – BP404T)
| Author’s Name | Dr. Vijay V. Navghare, Dr. Mohini C. Kuchekar |
| Editions | Latest Edition |
| Publishers | Technical Publications |
Pharmacology 1 Topic-wise Summary
1. General Pharmacology
a. Introduction to Pharmacology – Definition, historical landmarks and scope of pharmacology, nature and source of drugs, essential drugs concept, and routes of drug administration.
- Agonists, antagonists (competitive and non-competitive), spare receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, allergy.
b. Pharmacokinetics – Membrane transport, absorption, distribution, metabolism, and excretion of drugs.
- Enzyme induction, enzyme inhibition, kinetics of elimination.
General Pharmacology
a. Pharmacodynamics – Principles and mechanisms of drug action. Receptor theories and classification of receptors, regulation of receptors.
- Drug–receptor interactions, signal transduction mechanisms: G-protein–coupled receptors, ion channel receptors, transmembrane enzyme-linked receptors, transmembrane JAK–STAT binding receptors, and receptors that regulate transcription factors.
- Dose–response relationship, therapeutic index, combined effects of drugs, and factors modifying drug action.
b. Adverse drug reactions
c. Drug interactions (pharmacokinetic and pharmacodynamic)
d. Drug discovery and clinical evaluation of new drugs – Drug discovery phase, pre-clinical evaluation phase, clinical trial phase, phases of clinical trials, and pharmacovigilance.
2. Pharmacology of Drugs Acting on the Peripheral Nervous System
a. Organization and function of the ANS
b. Neurohumoral transmission, co-transmission, and classification of neurotransmitters
c. Parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics
d. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral)
e. Local anesthetic agents
f. Drugs used in myasthenia gravis and glaucoma
3. Pharmacology of Drugs Acting on the Central Nervous System
a. Neurohumoral transmission in the CNS with special emphasis on the importance of various neurotransmitters such as GABA, glutamate, glycine, serotonin, and dopamine
b. General anesthetics and pre-anesthetics
c. Sedatives, hypnotics, and centrally acting muscle relaxants
d. Anti-epileptics
e. Alcohols and disulfiram
4. Pharmacology of Drugs Acting on the Central Nervous System
a. Psychopharmacological agents: antipsychotics, antidepressants, anti-anxiety agents, anti-manics, and hallucinogens
b. Drugs used in Parkinson’s disease and Alzheimer’s disease
c. CNS stimulants and nootropics
d. Opioid analgesics and antagonists
e. Drug addiction, drug abuse, tolerance, and dependence