Pharmaceutical Organic Chemistry-II – Semester-III
| Author’s Name | Anup K Chakraborty, Abhishek Tiwari, Neeraj Upmanyu |
| Editions | First Edition |
| Publishers | Nirali Prakashan |
Pharmaceutical Organic Chemistry II for B. PHARMACY PCI
| Author’s Name | Sadhana Raul |
| Editions | Latest Edition |
| Publishers | Technical Publication |
TEXTBOOK OF PHARMACEUTICAL ORGANIC CHEMISTRY II (SEM III) B.PHARM
| Author’s Name | VARUN AND PRAGI ARORA |
| Editions | Latest Edition |
| Publishers | S VIKAS AND COMPANY (PV) |
Pharmaceutical Organic Chemistry-II Book for B.Pharm 3rd Semester
| Author’s Name | Dr. G. Geetha & Dr. Arvind Kumar Singh Dr. Arvind N. Lumbhani |
| Editions | Latest Edition |
| Publishers | Thakur Publication Pvt Ltd |
Pharmaceutical Organic Chemistry 2 Topic-wise Summary
Benzene and its derivatives
A. Analytical, synthetic, and other evidence in the derivation of the structure of benzene; orbital picture; resonance in benzene; aromatic characters; Huckel’s rule.
B. Reactions of benzene – nitration, sulphonation, halogenation (reactivity); Friedel-Crafts alkylation (reactivity, limitations); Friedel-Crafts acylation.
C. Substituents: Effect of substituents on reactivity and orientation of monosubstituted benzene compounds towards electrophilic substitution reactions.
D. Structure and uses of DDT, Saccharin, BHC, and Chloramine.
Phenols* – Acidity of phenols; effect of substituents on acidity; qualitative tests; structure and uses of phenol, cresols, resorcinol, and naphthols.
Aromatic Amines* – Basicity of amines; effect of substituents on basicity; synthetic uses of aryl diazonium salts.
Aromatic Acids* – Acidity; effect of substituents on acidity; important reactions of benzoic acid.
Fats and Oils
a. Fatty acids – reactions.
b. Hydrolysis, hydrogenation, saponification, and rancidity of oils; drying oils.
c. Analytical constants – Acid value, saponification value, ester value, iodine value, acetyl value, Reichert-Meissl (RM) value – significance and principles involved in their determination.
Polynuclear hydrocarbons
a. Synthesis and reactions.
b. Structure and medicinal uses of naphthalene, phenanthrene, anthracene, diphenylmethane, triphenylmethane, and their derivatives.
Cycloalkanes*
- Stabilities – Baeyer’s strain theory; limitations of Baeyer’s strain theory; Coulson and Moffitt’s modification; Sachse-Mohr’s theory (theory of strainless rings).
- Reactions of cyclopropane and cyclobutane only.