TEXTBOOK OF PHARMACEUTICAL ORGANIC CHEMISTRY
| Author’s Name | Mohammed Ali |
| Editions | Latest Edition |
| Publishers | CBS Publishers |
Pharmaceutical Organic Chemistry-1: First Year B. Pharm. / SEM-2
| Author’s Name | Dr. K. G. Bothara, Dr. S. Y. Gabhe |
| Editions | First Edition |
| Publishers | Nirali Prakashan |
PV PHARMACEUTICAL ORGANIC CHEMISTRY-I
| Author’s Name | SAPAN AND ARVIND VARUN, PRAGI |
| Editions | Latest Editions |
| Publishers | S VIKAS AND COMPANY (PV) |
Pharmaceutical Organic Chemistry 2 Topic-wise Summary
Classification, Nomenclature, and Isomerism
- Classification of Organic Compounds
- Common and IUPAC systems of nomenclature of organic compounds (up to 10 carbons, open-chain and carbocyclic compounds)
- Structural isomerisms in organic compounds
Alkanes, Alkenes, and Conjugated Dienes
- SP³ hybridization in alkanes, halogenation of alkanes, uses of paraffins.
- Stabilities of alkenes, SP² hybridization in alkenes.
- E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeff’s orientation and evidences.
- E1 versus E2 reactions, factors affecting E1 and E2 reactions.
- Ozonolysis, electrophilic addition reactions of alkenes, Markownikoff’s orientation, free radical addition reactions of alkenes, Anti-Markownikoff’s orientation.
- Stability of conjugated dienes, Diels-Alder reaction, electrophilic addition, free radical addition reactions of conjugated dienes, allylic rearrangement.
Alkyl Halides
- SN1 and SN2 reactions – kinetics, order of reactivity of alkyl halides, stereochemistry, and rearrangement of carbocations.
- SN1 versus SN2 reactions, factors affecting SN1 and SN2 reactions.
- Structure and uses of ethyl chloride, chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane, and iodoform.
Alcohols
- Qualitative tests.
- Structure and uses of ethyl alcohol, methyl alcohol, chlorobutanol, cetostearyl alcohol, benzyl alcohol, glycerol, and propylene glycol.
Carbonyl Compounds (Aldehydes and Ketones)
- Nucleophilic addition, electromeric effect, aldol condensation, crossed aldol condensation.
- Cannizzaro reaction, crossed Cannizzaro reaction, benzoin condensation, Perkin condensation.
- Qualitative tests.
- Structure and uses of formaldehyde, paraldehyde, acetone, chloral hydrate, hexamine, benzaldehyde, vanillin, and cinnamaldehyde.
Carboxylic Acids
- Acidity of carboxylic acids, effect of substituents on acidity, inductive effect, and qualitative tests for carboxylic acids, amides, and esters.
- Structure and uses of acetic acid, lactic acid, tartaric acid, citric acid, succinic acid, oxalic acid, salicylic acid, benzoic acid, benzyl benzoate, dimethyl phthalate, methyl salicylate, and acetylsalicylic acid.
Aliphatic Amines
- Basicity, effect of substituents on basicity, qualitative tests.
- Structure and uses of ethanolamine, ethylenediamine, and amphetamine.