Novel Drug Delivery System Important Questions are most helpful for the B.Pharm 7th semester examination. You can also download the suggestions PDF.
Controlled Drug Delivery System
1. Define Controlled Release DDS. List out their advantages and disadvantages.
2. Describe the rationale behind the development of controlled release formulations.
3. Explain the principles behind the development of controlled release formulations.
4. List out and briefly explain the factors influencing the design and performance of controlled release products.
5. Explain the physicochemical properties of drugs to be considered when selecting them for formulation into CR dosage forms.
6. Explain why the biological properties should be considered when selecting drug candidates for CR drug delivery systems.
7. Define dissolution controlled DDS. Explain the principles and approaches used in their design.
8. Explain the mechanism of drug release from diffusion controlled DDS. List out their advantages and disadvantages.
9. Explain the principle of drug release from bioerodible DDS and the parameters that can be controlled.
10. Explain an ion exchange controlled drug delivery system.
11. Define polymers. Briefly explain their role in the design of CR DDS.
12. Classify polymers with examples.
13. Elaborate on the applications of polymers in CR/SR DDS with suitable examples.
Microencapsulation
1. Define microencapsulation. List out the advantages and disadvantages of microencapsulation.
2. Explain the techniques of microencapsulation.
3. Explain the coacervation phase separation technique of microencapsulation.
4. Explain the Singer-Nicolson model for the mucosal membrane.
5. Explain the theories of mucoadhesion.
6. Write a short note on mucoadhesive polymers.
7. Explain various routes of transmucosal permeation.
8. What are the mechanisms and pathways for trans-mucosal permeation of drugs?
9. Enlist the advantages and disadvantages of buccal drug delivery.
10. List the ideal requirements of suitable drug candidates for buccal delivery.
11. Explain the approaches used in the design of mucoadhesive buccal DDS.
12. Classify and explain the design of buccal dosage forms.
13. Define implantable drug delivery system and how they are developed.
14. List out the advantages and disadvantages of Implantable Drug Delivery Systems.
15. Explain about different types of implants.
16. Explain the principle of drug release from implants and osmotic pumps.
Transdermal Drug Delivery System
1. Define TDDs. List out the advantages and limitations of TDDs.
2. Explain the different factors affecting percutaneous permeation of drugs.
3. Explain the various types of penetration enhancers used in TDDs to enhance percutaneous absorption.
4. Describe the basic components of TDDs.
5. Enlist the different transdermal devices and explain the polymer membrane moderated device.
6. Explain the matrix dispersion type of transdermal device.
7. Define gastro retentive drug delivery system (GRDDS). Explain the purposes and benefits of gastro-retentive drug delivery.
8. Explain the various factors that control the gastro retention of dosage forms.
9. Briefly explain the principle and design of the floating type of gastro retentive DDS.
10. Describe the design of expandable gastro retentive DDS.
11. Explain the design of the mucoadhesive type of gastro-retentive DDS.
12. Explain inflatable systems.
13. Write a note on Nasal Drug Delivery System.
14. Give the advantages and disadvantages of Nasal Drug Delivery System.
15. Give the applications of Nasal Drug Delivery System.
16. Enlist and explain the components of Nasal Drug Delivery System.
17. Write a note on Pulmonary Drug Delivery System.
18. Give the advantages and disadvantages of Pulmonary Drug Delivery System.
19. Define Aerosols. Enlist and explain one type of Aerosol used in Pulmonary Drug Delivery System.
20. Write a note on Metered Dose Inhalers.
21. What are Dry Powder Inhalers (DPIs)? Explain.
22. Enumerate on the Nebulizers and their types.
Targeted Drug Delivery System
1. Explain the Targeted Drug Delivery System. Add a note on concepts and components of Targeted Drug Delivery System.
2. Write about the different approaches used in Targeted Drug Delivery System.
3. Give the advantages and disadvantages of Targeted Drug Delivery System.
4. Define and classify Liposomes. Write about the structural components of Liposomes.
5. Give the advantages and disadvantages of Liposomes.
6. Enlist and explain any one method of preparation of Liposomes.
7. Enlist and explain the various methods for characterization of Liposomes.
8. Write about the applications of Liposomes.
9. Define Niosomes. Add a note on components of Niosomes.
10. Enlist and explain any one method for preparation of Niosomes.
11. Write about the applications of Niosomes.
12. Define Nanoparticles. Give the advantages and disadvantages of Nanoparticles.
13. Write a note on polymers used in the preparation of Nanoparticles.
14. Enlist the different methods and explain any one method for the preparation of Nanoparticles.
15. What are the characterization methods used in the evaluation of Nanoparticles?
16. Write a note on applications of Nanoparticles.
17. What are Monoclonal Antibodies? Add a note on characteristics of Monoclonal Antibodies.
18. Write about the advantages and disadvantages of Monoclonal Antibodies.
19. Explain the preparation of Monoclonal Antibodies.
20. Give the applications of Monoclonal Antibodies.
Ocular Drug Delivery System
1. Explain the Ocular Drug Delivery System and add a note on types of approaches used in it.
2. Enlist and explain the barriers to Ocular Drug Delivery System.
3. Enlist and explain the methods to overcome barriers to Ocular Drug Delivery System.
4. Write a note on the various formulations for Ocular Drug Delivery System.
5. Define and classify Inserts. Explain with suitable examples.
6. Write a note on IUDs.
7. Define and classify the various IUDs.
8. Give the advantages and disadvantages of IUDs.
9. Differentiate between Medicated and Non-Medicated IUDs.
10. What are Progestasert?
11. What is MIRENA?