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PHARMACOLOGY CHAPTER-WISE NOTES ER20-21T
CHAPTER – 1
General Pharmacology
Introduction and scope of Pharmacology
Various routes of drug administration – advantages and disadvantages
Drug absorption – definition, types, factors affecting drug absorption
Bioavailability and the factors affecting bioavailability
Drug distribution – definition, factors affecting drug distribution
Biotransformation of drugs – Definition, types of biotransformation reactions, factors influencing drug metabolisms
Excretion of drugs – Definition, routes of drug excretion
General mechanisms of drug action and factors modifying drug action
CHAPTER – 2
Drugs Acting on the Peripheral Nervous System
Steps involved in neurohumoral transmission
Definition, classification, pharmacological actions, dose, indications, and contraindications of
a) Cholinergic drugs
b) Anti-Cholinergic drugs
c) Adrenergic drugs
d) Anti-adrenergic drugs
e) Neuromuscular blocking agents
f) Drugs used in Myasthenia gravis
g) Local anaesthetic agents
h) Non-Steroidal Anti-Inflammatory drugs (NSAIDs)
CHAPTER – 3
Drugs Acting on the Eye
Definition, classification, pharmacological actions, dose, indications and contraindications of
Miotics
Mydriatics
Drugs used in Glaucoma
CHAPTER – 4
Drugs Acting on the Central Nervous System
Definition, classification, pharmacological actions, dose, indications, and contraindications of
General anaesthetics
Hypnotics and sedatives
Anti-Convulsant drugs
Anti-anxiety drugs
Anti-depressant drugs
Anti-psychotics
Nootropic agents
Centrally acting muscle relaxants
Opioid analgesics
CHAPTER – 5
Drugs Acting on the Cardiovascular System
Definition, classification, pharmacological actions, dose, indications,and contraindications of
Anti-hypertensive drugs
Anti-anginal drugs
Anti-arrhythmic drugs
Drugs used in atherosclerosis and
Congestive heart failure
Drug therapy for shock
CHAPTER – 6
Drugs Acting on Blood and Blood Forming Organs
Definition, classification, pharmacological actions, dose, indications, and contraindications of
Hematinic agents
Anti-coagulants
Antiplatelet agents
Thrombolytic drugs
CHAPTER – 7
Definition, classification, pharmacological actions, dose, indications, and contraindications of
Bronchodilators
Expectorants
Anti-tussive agents
Mucolytic agents
CHAPTER – 8
Drugs Acting on the Gastrointestinal Tract
Definition, classification, pharmacological actions, dose, indications, and contraindications of
Anti-ulcer drugs
Anti-emetics
Laxatives and purgatives
Anti-diarrheal drugs
CHAPTER – 9
Drugs Acting on the Kidney
Definition, classification, pharmacological actions, dose, indications, and contraindications of
Diuretics
Anti-Diuretics
CHAPTER – 10
Hormones and Hormone Antagonists
Physiological and pathological role and clinical uses of
Thyroid hormones
Anti-thyroid drugs
Parathormone
Calcitonin
Vitamin D
Insulin
Oral hypoglycemic agents
Estrogen
Progesterone
Oxytocin
Corticosteroids
CHAPTER – 11
Autocoids
Physiological role of Histamine, 5 HT and Prostaglandins
Classification, clinical uses, and adverse effects of antihistamines and 5 HT antagonists
CHAPTER – 12
Chemotherapeutic Agents: Introduction, basic principles of chemotherapy of infections, infestations and neoplastic diseases, Classification, dose, indication and contraindications of drugs belonging to the following classes:
Penicillins
Cephalosporins
Aminoglycosides
Fluoroquinolones
Macrolides
Tetracyclines
Sulphonamides
Anti-tubercular drugs
Anti-fungal drugs
Anti-viral drugs
Anti-amoebic agents
Anthelmintics
Anti-malarial agents
Anti-neoplastic agents
CHAPTER – 13
Biologicals
Definition, types, and indications of biological agents with examples
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