4th Semester B Pharm New Syllabus – 2022 Online Free PDF Download

4th Semester B Pharm New Syllabus – 2022 includes both theoretical subjects as well as practical classes. Here we provide the latest Bachelor Of Pharmacy Syllabus & Subjects as mentioned by the Pharmacy Council of India (PCI).

From this B. Pharm PCI Syllabus 2021-22 Pdf additionally, you will get exact PT or Subjects Code for every subject of theory as well as practical. You can read the Syllabus for B. Pharm AICTE or download it in PDF format given below the link.

Topic NameSyllabus Pdf
4th Semester B Pharm New SyllabusClick Here To Download

4th Semester B Pharm New Syllabus Online

4th Semester B Pharm New Syllabus of Second Year latest AICTE approved PCI syllabus are given below which is also the same as MAKAUT B. Pharm 4th Semester Syllabus. The fourth semester includes a total of five subjects. All five subjects are mandatory.

4th Semester B Pharm New Syllabus PDF 2021 Free Download
4th Semester B Pharm New Syllabus

Pharmaceutical Organic Chemistry-III Syllabus

4th Semester B Pharm New Syllabus having of Pharmaceutical Organic Chemistry-III is most important from freshers’ point of view. Most of the students don’t know what are the B Pharmacy 2nd year Subjects and Syllabus?

Here we provide the new Pharmaceutical Organic Chemistry-II whole B Pharmacy 4th Sem Syllabus Pdf. This syllabus is the same as with Pharmacy Council of India (PCI) provided syllabus.

Theory (PT- 414)


• Stereoisomerism

Stereoisomerism, Optical Isomerism, Optical activity of the isomerisms, diastereoisomerism, enantiomerism, meso compounds, elements of the symmetry, Achiral and Chiral stereo molecules.

DL System of nomenclature of the optical isomerism with optical activity, RS System of nomenclature, Chiral molecules reactions, Racemic Mixture resolution, and racemic modification, Asymmetric Synthesis- absolute and partial Stereoisomerism.


• Geometrical Isomerism

Nomenclature of the geometrical isomerism (Cis, Trans, EZ, Syn, and Anti Systems of Isomerism), methods of the determination of the configuration of geometrical isomerisms, Conformational Isomerism in Ethane, normal butane, cyclohexane, and other compounds,

Stereoisomerism of the Compounds of Biphenyl (also called Atropisomerism), and Optical activity condition, Stereospecific and Stereoselective Reactions of Isomerism.


• Heterocyclic Compounds

Nomenclature and Classification of the Heterocyclic Compounds, Synthesis, Reactions, and Medicinal Uses of following compounds derivatives such as Pyrrole, Furan, and Thiophene, Relative aromaticity and reactivity of the above compounds.


Synthesis, reactions, and Medicinal Use of the following compounds such as Pyrazole, Imidazole, Oxazole, and Thiazole, Pyridine, Quinoline, Isoquinoline, Indole, and Acridine, Basicity of the Pyridine with synthesis and medicinal uses such as Pyrimidine, Azepines, Purine, and their derivatives.


• Reactions Of the Synthetic Importance

Reactions of Metal Hydride Reduction (NaBH4 and LiAlH4 ), Importance name reactions are Clemmensen reduction, Wolf Kishner reduction, Birch reduction, Oppenauer-Oxidation, Dakin Reactions, Claisen-Schmidt Condensation, Beckmann’s rearrangement, and Schmidt rearrangement.

Industrial Pharmacy-I Syllabus

Industrial Pharmacy-I is the other most important subject which syllabus described are in below. 4th Semester B. Pharm New Syllabus can read online here or B Pharm 4th Sem Syllabus GTU Pdf can download above-given link. This syllabus is the same as with Pharmacy Council of India (PCI) provided syllabus.

Theory (PT- 413)


• Preformulation Studies- Introduction to the Preformulation Studies, Its goals and objectives, Study of the physicochemical characteristics of the drugs substances.

A) Physical Properties- Physical form (Crystal and Amorphous), Particles size, shape, flow properties, solubility (pKa, pH, Partition coefficient), and Polymorphism.

B) Chemical Properties- Hydrolysis, Oxidation, Reduction, Racemization, Polymerization BCS (Biopharmaceutical Classification System) classification of drugs and significance,

Application of the preformulation consideration in the development of solid, liquid oral, and parenteral dosage forms & its impact on the stability of the dosage forms.


• Tablets

A. Tablets Introduction, ideal characteristics, and classification, Excipients, formulation of tablets, granulation methods, compression and processing problems, equipment, and tablet tooling.

B. Tablet coating- Types of coating, coating materials, formulation of the coating composition, equipment employed, methods of coating, and defects in the coating.

C. Quality control tests- In processing & finished products tests.

• Liquid Orals in pharmaceutical- Formulation methods & manufacturing methodology of the liquid orals such as syrups and elixirs suspension and emulsions, Packaging and filling, evaluation of liquid orals official in the pharmacopeia standard.


• Capsules

A) Hard Gelatin Capsules- Introduction of capsules, production of Hard Gelatin capsule shells, size of capsules, finishing, filling, and special techniques of formulation of Hard gelatin capsules, manufacturing defects, In processing and final products quality control test for capsules.

B) Soft Gelatin Capsules- Nature of shell & soft gelatin capsules content, size of the capsules, Importance of base adsorption and minim or grams factors, production, in-process and final products quality control test, packaging, storage, and stability testing of soft gelatin tablet capsules, and their applications.

• Pellets- Introduction to pellets, formulation requirements, pelletization process, equipment for manufacturers of pellets.


• Parenteral Products Details

A) Definition, types, advantages, and limitations of the parenteral products, preformulation factors studies, essential requirements, vehicles, additives, and the importance of isotonicity of the parenteral products.

B) Procedure of production, production facilities, and controls, aseptic processing.

C) Formulation of different injections, sterile powders, large volume parenteral and lyophilized products.

D) Parenteral products containers and closure selection of the parenteral products, filling, sealing of ampoules, vials & infusion fluids, quality control test of parenteral products details.

• Ophthalmic preparations– Definition and introduction, formulation considerations, formulation of eye drops, eye ointments, and eye lotions, methods of preparation, labeling, evaluation of the Ophthalmic preparation.


• Cosmetics– Formulation and preparation of the cosmetics preparation, lipstick, shampoos, cold cream, vanishing cream, toothpaste, hair dyes, and sunscreens.

• Pharmaceutical Aerosols– Definition, introduction, propellants, valves, types of aerosols system, formulation and manufacture of aerosols, evaluation of aerosols, quality control, and stability studies.

• Packaging Materials Science– Packaging Materials used for the pharmaceutical products, factors influencing the choice of containers, legal and official requirements for containers, stability aspects of the packaging materials, quality control tests of packaging materials.

Practical (PT- 493)

I) Preformulation Studies on paracetamol or aspirin or any other drugs.

II) Preparation and evaluation of paracetamol tablets.

III) Preparation and evaluation of the aspirin tablets.

IV) Coating of tablets- film coating of tablets or granules.

V) Preparation and evaluation of Tetracycline capsules.

VI) Preparation of calcium Gluconate injections.

VII) Preparation of Ascorbic Acid Injections.

VIII) Quality Control tests of marketed tablets and capsules.

IX) Preparation of eye drops or and eye ointments.

X) Preparation of creams cold or vanishing cream.

XI) Evaluation of glass containers.

Physical Pharmaceutics-II Syllabus

Physical Pharmaceutics-II is the other most important subject which syllabus described are in below. 4th Semester B Pharm New Syllabus can read online here or B. Pharm 4th Sem Syllabus Pdf download above-given link. This syllabus is the same as with AKTU b. Pharm 4th year Syllabus 2022-23 provided syllabus.

Theory (PT- 416)


• Colloidal Dispersion

Dispersed System Classification and their general characteristics, Size and shape of colloidal particles, Colloids classification and comparative account of their general physical properties such as Optical, Kinetics, and electrical properties, Effect of electrolytes, Peptizations, Coacervation, and Protective actions.


• Rheology

Definition of Rheology, Newtonian Systems, the law of flow, kinematic viscosity, Non-Newtonian System, the effect of temperature, Pseudoplastic, Dilatant, Plastic, Thixotropy, Thixotropy in Formulation, Determination of the Viscosity, Falling Sphere, Capillary, and Rotational Viscometers.

• Deformation of Solids

Plastic and elastic deformation system, Heckel equations, Stress, Strain, and Elastic modulus.


• Course Dispersion

Coarse Dispersion including Suspensions, Interfacial Properties of Suspended Particles, Settling in Suspension, Formulation of Flocculatted and Deflocculated Suspensions, Emulsions and theories of emulsification,

Microemulsion and Multiple Emulsions, Stability of the emulsions, Preservation of the emulsions, The Rheological properties of emulsions & formulation by HLB method.


• Micromeritics

Micromeritics Definitions, Particles size and distribution, mean particle size, number & weight distribution, particles numbers, Methods for determining particles size by various methods, counting and separation method,

Specific surface, particles shape, a method for determination of surface area, permeability, adsorption, derived properties of powders, packing arrangements, porosity, densities, Bulkiness and flow Properties.


• Drug Stability

Stability of drug Introduction, reactions of kinetics, Zero-order, pseudo-zero, first and second order, units of basic rate constants, determination of reaction order, Physical & Chemical factors influencing the chemical degradation of the pharmaceutical products; such as Temperature, Ionic strength,

Solvent, Dielectric Constants, Specific and General acid-base catalysis, Simple numerical problems, Stabilization of the medicinal agents against the common reactions like Oxidation and Hydrolysis, Accelerated stability testing of the drugs in the expired of pharmaceutical dosage forms, Photolytic degradation, and prevention.

Practical (PT- 496)

  1. Determination of the particles size, and particles distribution using the sieving method.
  2. Determination of the particle’s size, and particles distribution using the microscopic method.
  3. Determination of the bulk density, porosity, and true density.
  4. Determination of the angle of repose and influencing of lubricants on the angle of repose.
  5. Determine if the viscosity of liquids using Ostwald’s viscometers and others.
  6. Determine the sedimentation volume with the effect of suspending and other agents.
  7. Determination of the sedimentation volume (SV) with the effect of various concentrations of a single (one) suspending agents.
  8. Determine if the viscosity of semisolid using the Brookfield viscometers and others.
  9. Determination of reactions rate constants of first-order reactions.
  10. Determination of reaction rate constants of second-order reactions.
  11. Determination of the accelerated stability studies.

Pharmacology-I Syllabus

Pharmacology-I is the other most important subject which syllabus described are in below. 4th Semester B Pharm New Syllabus can read online here or B Pharm 4th Sem Syllabus Makaut Pdf can download above-given link. This syllabus is the same as with B. Pharm 4th Sem Syllabus PCI provided syllabus.

Theory (PT- 418)


• General Pharmacology

A. An Introduction to the Pharmacology– Pharmacology Definition, historical landmark, the scope of Pharmacology, nature, and sources of the Pharmacological drugs agents, essential drugs concept with routes of the drug administration,

Agonists, Antagonist (Competitive and the Noncompetitive), Addiction, Tolerance, Dependence, Tachyphylaxis, Idiosyncrasy, Allergy.

B. Pharmacokinetics– Definition of pharmacokinetics, membrane transport, absorption, distribution, metabolism and excretion, Enzymes induction, Enzyme inhibition, and Kinetics of elimination.


• General Pharmacology

A. Pharmacodynamics– Principles and mechanisms of drug action in pharmacodynamics, Receptor theories and classification of receptors, receptors regulation, drug receptors interactions signal transduction mechanisms,

G-protein coupled receptors, Ion-channel receptors, transmembrane enzyme-linked receptors, transmembrane JAK-STAT binding receptor, receptors which regulates transcription factors, dose-responsive relationship, therapeutic index, combined effects of drugs and factors modifying drug action.

B. Adverse Drug Reactions.

C. Drug Interactions in between Pharmacokinetics and Pharmacodynamics.

D. Drug discovery and clinical evaluation of new drugs- Drug discovery phase, Pre-clinical evaluation phase, Clinical trial phase, Phases of clinical trials, and Pharmacovigilance.


• Pharmacology of the Drugs Acting on Peripheral Nervous System (PNS)

  • Organization and the function of the Automatic Nervous System (ANS) in Pharmacology.
  • Neurohormonal transmission, co-transmission of drugs, and classification of important neurotransmitters.
  • Parasympathomimetics, Parasympatholytics, Sympathomimetics, and sympatholytics in Pharmacology.
  • Neuromuscular blocking agents and skeletal muscles relaxants.
  • Local anesthetic agents.
  • Drugs used in myasthenia gravis and glaucoma.


• Pharmacology of drugs acts the Central Nervous System (CNS)

  • Neurohormonal transmission of drugs in the Central Nervous System (CNS) special emphasis on the importance of various neurotransmitters like Glycine, Glutamate, GABA, Serotonin, Dopamine.
  • General anesthetic and pre-anesthetics.
  • Hypnotics, Sedative, and Central acting muscle relaxants.
  • Anti-epileptics drugs.
  • Alcohols and Disulfiram.


• Pharmacology of drugs acting on Central Nervous System (CNS)

  • Agents of Psychopharmacological – Antipsychotics, Anti-manics, Antidepressants, Anti-anxiety agents, and hallucinogenic agents.
  • Drugs or agents used in Alzheimer’s and Parkinson’s diseases.
  • Central Nervous System (CNS) stimulants and nootropics.
  • Opioid analgesics, agonist, and antagonists.
  • Drugs addiction, drug users, dependence, and tolerance.

Practical (PT- 498)

a) Introduction to the experimental pharmacology in laboratory animals.

b) Commonly used in instruments in experimental pharmacology laboratory animals.

c) Studies of the common Pharmacology laboratory animals like rats, rabbits, and mice.

d) Pharmacological Maintenance of the pharmacology laboratory animals as per CPCSEA guidelines rules.

e) Common laboratory techniques, Blood withdrawal, serum, plasma separation, anesthetia used for animal studies.

f) Study of the different routes of drugs administration in experimental mice or rats.

g) Study of the effect of hepatic microsomal enzymes inducers on the phenobarbitone sleeping time in mice.

h) Effects of the drugs or drugs agents on ciliary motility of frogs oesophagus.

i) Effect of the drugs on the rabbit eye.

j) Effects of the skeletal muscle relaxants using rota-rod apparatus.

k) Effect of the drugs or drugs agents on locomotor activities using an actophotometer.

l) Anticonvulsant effect of drugs by MES and PTZ method.

m) Study of stereotype and anti-cationic activity of drugs on rats or mice.

n) Study of anxiolytic activity of drugs using rats or mice.

o) Study of the local anesthetic by different methods.

[“All laboratory techniques used and experimental animals are used demonstrated by simulated experiments by the different software and videos in pharmacological laboratory”]

Pharmacognosy and Phytochemistry-I

Pharmacognosy and Phytochemistry-I is the other most important subject which syllabus described are in below. 4th Semester B Pharm New Syllabus can read online here or B Pharm 4th Semester Syllabus AKTU Pdf can download above-given link. This syllabus is the same as with Pharmacy Council of India (PCI) provided syllabus.

Theory (PT- 412)


• Introduction to the Pharmacognosy

A) Definitions, History, Scope, and development of pharmacology.

B) Sources of the drugs- Plants, Animals, Marine, and Tissue culture.

C) Pharmacognosy Organized Drugs, unorganized drugs such as dried latex, dried extracts, dried juices, gums, mucilages, oleoresins, oleo-gum-resins, and others various compounds.

• Classification of the Drugs

Alphabetical, morphological, taxonomical, chemical, pharmacological, chemo, and sero taxonomical classification of the drugs.

• Quality Control of drugs of the Natural origin

Adulteration of the drugs from the natural Origin, the Evaluation process of drugs by the various methods like organoleptic, microscopic, physical, chemical, and biological various methods and properties,

Quantitative microscopy of crude drugs including others plants like Lycopodium Spore Method, Leaf constants methods, Camera Lucida plants and diagrams of microscopic objects plants with camera lucida.


• Collection, Cultivation, Processing, and Storage of drugs from natural Origin plants

Pharmaceutical Cultivation and collection of the drugs from natural origin plants, factors influencing cultivation of the medicinal plants, plant hormones and of their applications with uses, polyploidy, mutation, and hybridization with the reference of the medicinal plant’s drugs.

• Conservation of Medicinal Plants various methods


• Plant tissues Culture

Historical development of the plant tissue culture, types of plant tissue cultures, nutritional requirements for PTC, growth, and their maintenance, Application of Plant Tissues Culture (PTC) in pharmacognosy, Edible vaccines of plant tissue culture.


• Pharmacognosy in the various systems of medicine

Role Of Pharmacognosy and phytochemistry in the various systems like allopathy and traditional systems of medicine namely, Ayurveda, Siddha, Unani, Homeopathy, and the Chinese system of ancient medicine.

• Introduction to the secondary metabolites

Introduction and Definitions of the secondary metabolites, classification, properties, and tests for the identification of alkaloids, gum, glycosides, flavonoids, tannins, volatile oils, and resins secondary metabolites.


Study of the biological sources, chemical nature, and uses of drugs of natural origin containing the following drugs.

• Plant Products

Fibers: Jute, Cotton, Hemp, Hallucinogens, Teratogens, and Natural allergens.

• Primary Metabolites

Primary metabolites General introduction, detailed study of the chemistry, sources, preparation, evaluation, preservation, therapeutic uses, storage, and commercial significance as pharmaceutical aids and medicines for the above following primary metabolites.

• Carbohydrates– Acacia, Agar, Tragacanth, Honey.

• Proteins and Enzymes– Gelatin, Casein, proteolytic enzymes such as papain, bromelain, serratiopeptidase, urokinase, Pepin, and streptokinase.

• Lipids (Waxes, fats, fixed oils)– Primary metabolites are Castor oil, Chaulmoogra oil, Wool fat, Bee Wax.

• Marine Drugs– Novel medicinal agents from marine sources of drugs.

Practical (PT- 492)

i) Analysis of the crude drugs by the different chemical test- (a) Tragacanth (b) Acacia (c) Gelatin (d) Agar (e) Starch (f) Honey (g) Castor Oil.

ii) Determination of the stomatal number and stomatal index.

iii) Determination of vein islet number, vein islet termination, and palisade ratio.

iv) Determination of the pharmaceutical size of starch grains, Calcium oxalate crystals by the eyepiece of a micrometer in the laboratory.

v) Determination of fiber width and length.

vi) Determination of the number of starch grains by the Lycopodium Spore Method.

vii) Determine the Ash Value.

viii) Determination of the extractive values of crude drugs.

ix) Determination of the moisture content in the crude drugs.

x) Determination of the swelling index and foaming.

Which is the main subjects in B Pharm 4th Semester?

4th Semester B Pharm New Syllabus includes Practical and Theoritical both of the five mandatory Subjects are:
• Pharmaceutical Organic Chemistry-III
• Physical Pharmaceutics-II
• Industrial Pharmacy-I
• Pharmacology-I
• Pharmacognosy and Phytochemistry-I

Which is the syllabus of B Pharm 2n Year?

Here we provide the 4th Semester B Pharm New Syllabus, but also mentioned B Pharm 2nd Year Syllabus. Which includes two Semesters. All the Semesters have different Subjects.
Semester I includes major Subjects are:
• Human Anatomy and Physiology-I
• Pharmaceutical Analysis
• Pharmaceutical Inorganic Chemistry
• Pharmaceutics-I
Semester II includes major subjects are:
• Human Anatomy and Physiology-II
• Pharmaceutical Organic Chemistry-I
• Biochemistry
• Pathophysiology

Which is an optional subjects in b pharmacy?

4th Semester B Pharm New Syllabus topics cover all the subjects includes in the 4th Semester. There are no optional subjects, all subjects essential for study and university takes the examination. Pharmaceutical Organic Chemistry III having only theory but is essential for the upcoming semester.

Is there a B Pharm program in South Africa?

B Pharm undergraduate degree course is also accredited in South Africa various universities. Here we are providing the 4th Semester B Pharm New Syllabus, students also after completion of the D. Pharmacy course by PCI of India can apply through lateral entry accordingly.

Which is the Syllabus of Punjabi University for Pharmacy?

For the syllabus of the Punjabi University, we provide the 4th Semester B Pharm New Syllabus article where you will get the whole syllabus for reading online or can download pdf above the given link. We also mentioned theoritical and practical subjects at Punjab University, Patiala.

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